DURAClone IM TCRs

Mature T cells express T cell receptors (TCRs) that enable low affinity-recognition of antigens bound to major histocompatibility complex (MHC) molecules. Two forms of TCRs are known either consisting of heterodimers of variable α and β protein chains or γ and δ protein chains. The proportion of these two subpopulations are considered important in immunity and tolerance with mechanisms still under investigation. The DURAClone IM TCRs panel allows for assessment of TCR αβ and TCR γδ protein chain expression and detection of Vδ1+ and Vδ2+ subsets among TCRγδ+ T cells. It utilizes dry reagent technology that confers workflow improvements.

  • Combination of 9 markers in fluorochrome combinations that provide robust population identification, including CD3, CD4, CD8, CD45, HLA-DR, TCR αβ, TCR γδ, TCR Vδ1, TCR Vδ2
  • Pre-formulated antibody panel in a unitized assay eliminating antibody cocktailing
  • 25 tests per kit including 3 compensation kits with lot matched tandem dyes

For Research Use Only. Not for use in diagnostic procedures.

Features

Expert Panels

Efficiency

  • Eliminate time spent in titrating different antibody lots
  • Avoid waste that comes from preparing cocktail master mix
  • Simplify inventory management

Consistency

Easy to Use

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Technical Documents

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