Helios Antigen
Helios belongs to the Ikaros transcription factor family. Members of this family are DNA binding proteins containing two-zinc finger N terminal domains and protein binding domain. Helios expression is restricted to the T lymphocytes lineage. Helios is suggested to play an important role in CD4+CD25+FoxP3+ regulatory cells. It has been shown that Helios up-regulates the expression of FoxP3 expression by binding to the FoxP3 promoter. Helios is a highly conserved transcription factor that has 97% sequence homology between human and mice.
Clone: 22F6 | Isotype: IgG Hamster |
The clone 22F6 reacts with human and mouse Helios. | |
Choose a Helios Model
Product Line Specifications
Format | Liquid |
Specificity | Helios |
Form | Pacific Blue* |
Clone | 22F6 |
Isotype | IgG Hamster |
Target Species | Human |
Flow Product Line | IOTest |
Item Specifications Referenced | B49311 |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.