Valita Titer Assay vs. Traditional IgG Measurement Technologies

The accurate, rapid and high-throughput measurement of immunoglobulin G (IgG) is essential in the development and subsequent manufacture of therapeutic antibodies.

However, with some IgG measurement methods—such as ELISA and Protein A HPLC—it may take hours to obtain results due to tedious sample prep and the need for multiple reagents. And when you’re processing hundreds or thousands of clones to generate a commercially viable cell line, those hours add up and add unnecessary complexity to your workflow.

With the Valita Titer assay, there’s no sample prep, additional reagents or wash required. Because of that, you’ll be able to prepare and measure a full 96- or 384-well plate in as little as 15 minutes.

Valita Titer Assay, ELISA, HPLS and BLI comparison table


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Comparison of Analysis Attributes

Available in 96- and 384-well plate formats, and in two detection range formats—2.5 – 100 mg/L and 100 -2000 mg/L— the Valita Titer assay enables rapid, high-throughput IgG quantification directly from crude cell culture samples. The charts below compare IgG quantification in crude culture samples using the Valita Titer assay, biolayer interferometry (BLI), Protein A HPLC and ELISA.

valitatiter technology comparison


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Insightful Resources

valitatiter application note
Technical Note
Rapid Rabbit IgG Quantification using the Valita Titer Assay

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Valita Titer Assay Brochure

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Learn More About the Valita Titer Assay

Introducing Valita Titer Assays

Valita Titer plate-based, 96- and 384-well assays that offer a rapid, cost-effective way to measure IgG

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Automate With Ease

Easily integrate Valita Titer into your automated liquid handler and microplate reader

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Cell Line Development Webinar

Speed up your clone selection process with the Valita Titer assay

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Say Goodbye to Sample Preparation

Measure IgG titer straight from cell culture samples—no sample prep, additional reagents or wash required

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Future of Bioprocessing

Let's dive into the world of monoclonal antibodies and explore the solutions that pave the way for innovative and effective therapeutics.

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